Antiepileptic drug interactions. Part 1: Mutual interactions between antiepileptic drugs
نویسندگان
چکیده
منابع مشابه
Clinically relevant drug interactions with antiepileptic drugs.
Some patients with difficult-to-treat epilepsy benefit from combination therapy with two or more antiepileptic drugs (AEDs). Additionally, virtually all epilepsy patients will receive, at some time in their lives, other medications for the management of associated conditions. In these situations, clinically important drug interactions may occur. Carbamazepine, phenytoin, phenobarbital and primi...
متن کاملPharmacokinetic interactions between contraceptives and antiepileptic drugs
The occurrence of bi-directional drug interactions between antiepileptic drugs (AEDs) and combined oral contraceptives (OCs) pose potential risks of un-intended pregnancy and as well as seizure deterioration. It is well established that several of the older AEDs (carbamazepine, phenytoin and phenobarbital), are strong inducers of the hepatic cytochrome P450 (CYP) 3A4 enzyme system, and are asso...
متن کاملInteractions between antiepileptic drugs and hormones
Antiepileptic drugs (AEDs) are known to have endocrine side effects in both men and women. These can affect fertility, sexuality, thyroid function, and bone health, all functions of major importance for well-being and quality of life. The liver enzyme inducing antiepileptic drugs (EIAEDs), like phenobarbital, phenytoin, and carbamazepine, and also valproate (VPA), a non-EIAED, are most likely t...
متن کاملAntiepileptic Drugs Combination Therapy And Interactions
antiepileptic drugs combination therapy and interactions antiepileptic drugs combination therapy and interactions this page intentionally left blank chuyên khoa than antiepileptic drugs combination therapy and interactions josé e. cavazos, md phd san antonio va epilepsy center of 40 combination therapy in epilepsy : what, when, how and the importance of drug interactions in epilepsy therapy dru...
متن کاملBehavioral interactions between opiate and antiepileptic drugs in the mouse.
Morphine and related opioid compounds are known to possess proconvulsant activity based upon both electroencephalographic and behavioral criteria. The present authors previously suggested that opiate-related seizures were behaviorally inhibitory, and this was further investigated in the present study. The effects of pretreatment with three pharmacologically distinct compounds (sodium valproic a...
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ژورنال
عنوان ژورنال: Klinická farmakologie a farmacie
سال: 2016
ISSN: 1212-7973,1803-5353
DOI: 10.36290/far.2016.030